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In a 2014 case study, Webber et al. examined a 10-year-old girl with comorbid misophonia, OCD, and Tourette syndrome, highlighting the clinical and neurobiological overlap among these conditions. The patient showed intense distress and behavioral outbursts to auditory triggers, compulsive responses to tactile and auditory stimuli, and sensitivities across multiple sensory domains. Webber concluded that misophonia may be an aversive disorder, distinct from OCD, but likely sharing neural substrates such as dysfunction in the limbic system, basal ganglia, and auditory cortex, with dopaminergic and serotonergic dysregulation contributing to the symptom overlap. (Webber et al., 2014)