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utility of studying clinical symptoms in non- clinical un diagnosed samples in general and in misophonia specifically

Medinicoff 2022 noted several justifications for the utility of studying non-diagnosed people who show characteristics of a disorder, focusing specifically in the context of misophonia.  first they noted that Misophonia reactions likely existing on a spectrum in the general  population , so there is a basic science interest in understanding this spectrum of experience. Second , there is a long history of science using non-clinical populations that exhibit symptoms to identify characteristics/biomarkers, etc. that inform the mechanistic sources of a disorder. only studying diagnosed populations can cause ambiguity about the if biomarkers are tide to the mechanics of a disorder, or are simply the result of treatment./ having a chronic condition. lastly they note how observing naturalistic coping mechs in non diagnosed people with mild-moderate symptoms can inform efforts to treat more severe cases (Mednicoff et al., 2022)