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- The relationship between cognitive disengagement syndrome and misophonia in children with attention deficit hyperactivity disorder
- (Gercek et al., 2025)
- Misophonia
- ADHD
- CDS
- SCT-SR
- A-MISO-S-R
- T-DSM-IV-S
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The relationship between cognitive disengagement syndrome and misophonia in children with attention deficit hyperactivity disorder: the mediating role of cognitive disengagement syndrome symptoms
Status:: #status/complete
Metadata
- Item Type: #journalArticle
- Authors: Hacer Gizem Gercek, Borte Gurbuz Ozgur, Zahittin Hayta, Asiye Sapanca, Hatice Aksu,
- Date Added: August 20, 2025
- URL: https://annals-general-psychiatry.biomedcentral.com/articles/10.1186/s12991-025-00583-9
- DOI: 10.1186/s12991-025-00583-9
- Cite Key: gercekRelationshipCognitiveDisengagement2025
- Tags: #Misophonia, #clinical #ADHD, #cognitive-disengagement-syndrome, #sluggish-cognitive-tempo , #Adolescent
- PDF Attachments
Abstract
| Background/Purpose | Background- • Misophonia is increasingly recognized as distinct from general sound sensitivity disorders like hyperacusis. • Often comorbid with internalizing disorders (anxiety, depression), with less research on externalizing comorbidities. • Links between ADHD and sensory sensitivity have been noted, but associations with misophonia are unclear. • CDS is conceptually and phenomenologically related to inattention and internalizing symptoms, but has not been studied in relation to misophonia. Purpose- • Investigate the prevalence and severity of misophonia symptoms in adolescents with ADHD vs. controls. • Examine the relationship between misophonia, ADHD symptom dimensions (inattention vs. hyperactivity), and CDS. • Test whether CDS symptoms mediate the relationship between ADHD-inattention and misophonia. |
| Participants/samples | • N = 103 adolescents (53 with ADHD, 50 healthy controls). • Ages 12–18, recruited from two outpatient clinics in Türkiye. • ADHD group: diagnosed per DSM-5 via K-SADS-PL interviews. • Exclusion: comorbid psychiatric diagnoses (depression, anxiety), chronic medical conditions. |
| Measures | • ADHD symptoms: Turgay DSM-IV-Based Disruptive Behavior Disorders Scale (T-DSM-IV-S), parent-reported. • Misophonia: Amsterdam Misophonia Scale-Revised (AMISOS-R), adolescent self-report. • CDS symptoms: Sluggish Cognitive Tempo Self-Report Scale (SCT-SR), adolescent self-report. |
| Procedures | • Participants completed AMISOS-R and SCT-SR. • Parents of participants completed the T-DSM-IV-S. • K-SADS-PL interviews used to confirm diagnoses. • Statistical analyses included correlation, regression, and mediation analysis via bootstrapping. |
| Results | • ADHD group had significantly higher misophonia (AMISOS-R) scores than controls. • Misophonia severity positively correlated with: • T-DSM-IV-S inattention (r = 0.513), • T-DSM-IV-S hyperactivity/impulsivity (r = 0.291), • SCT-SR (r = 0.661). • Regression analysis: inattention (β = 0.833, p < 0.001) was the only independent predictor of misophonia severity. • Mediation analysis confirmed that CDS symptoms partially mediated the inattention–misophonia relationship (indirect effect: b = 0.37, 95% CI [0.22, 0.54], p < 0.018). |
| Discussion/Limits | Conclusion- • ADHD and CDS symptoms are associated with increased misophonia severity. • Inattention is the strongest ADHD-related predictor of misophonia. • CDS symptoms act as a partial mediator, suggesting shared neurocognitive or affective vulnerabilities. • Misophonia may be best conceptualized as a transdiagnostic issue linked to attentional and internalizing symptomatology. |
| Limitations:: | • Small sample size limits generalizability. • Cross-sectional design precludes causal inference. • Reliance on parent-report for ADHD symptoms; no adolescent self-report data. • used the Amsterdam scale ( that i am not a fan of) |
| Future Directions:: | • Larger longitudinal studies to explore causal pathways and effects of ADHD medication on misophonia. • Examine CDS as a transdiagnostic vulnerability factor in neurodevelopmental and internalizing conditions. • Investigate treatment targets addressing both misophonia and CDS in ADHD populations. |
| Relevance:: | • looked at the correlation between Misophonia and several comorbidities of interest including ADHD, and cognitive disengagement syndrome. • a good source on the Misophonia-attention link from a clinical perspective as well as as a good source for a ( at the time of my reading ) new to me concept of cognitive disengagement syndrome. |
Notes
key terms and concepts
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Misophonia – A condition marked by strong emotional and physiological reactions to specific, often human-generated, repetitive sounds (e.g., chewing, breathing), leading to avoidance and social impairment.
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ADHD (Attention Deficit Hyperactivity Disorder) – A neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity, and impulsivity.
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CDS (Cognitive Disengagement Syndrome) – Formerly known as sluggish cognitive tempo (SCT); involves hypoactivity, low alertness, daydreaming, apathy, and mental confusion.
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SCT-SR – Self-report scale measuring symptoms of sluggish cognitive tempo in adolescents.
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AMISOS-R – Amsterdam Misophonia Scale-Revised; assesses severity of misophonia.
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T-DSM-IV-S – Parent-report scale evaluating ADHD symptoms, based on DSM-IV criteria.
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Trigger Types and Emotions
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Most common misophonia triggers: eating, breathing, throat clearing.
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Predominant emotional responses: irritability, restlessness, followed by disgust and anxiety.
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No gender or age differences in misophonia severity found in this clinical sample.
Clinical Implications
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Misophonia symptoms in ADHD may go unrecognized; inclusion in clinical assessment could improve treatment planning.
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CDS may amplify misophonia symptoms through attentional and affective dysregulation mechanisms.