moderate Misophonics often lacking comorbidities is dispositive of comorbidities as a cause

Andermane et al. (2023), in a preregistered online study of 1430 participants (a subset of 419 completing clinical measures) grouped by cluster analysis into non-misophonic, moderate, and severe misophonia, found that clinical comorbidities were largely confined to the severe group, with the moderate group often returning sensitive null results on the Autism Spectrum Quotient (AQ), Anxiety Sensitivity Index (ASI-3), and Obsessive-Compulsive Inventory (OCI). Because the moderate group experiences misophonia yet frequently lacks these comorbidities, the authors reasoned that the comorbidities are unlikely to be a primary cause of the condition. They concluded that these comorbidities are not a primary cause but may instead play a role in the transition to a more severe profile (Andermane et al., 2023b).