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case of post-surgical acquired Misophonia

in their 2023 case report, Dappen describes the case of acquired Misophonia following surgical resection of the right posterior insula and adjacent auditory and sensory cortices for drug resistant epilepsy. among a collection of auditory perceptual changes the patient reported symptoms fitting the description of Misophonia that she did not have before the surgery. among there discussion of the implications for affected brain areas for broader musical and auditory perception, the authors conclude the posterior insula may play a previously underappreciated role in regulating emotional responses to sound and auditory social cues, especially those found Misophonia. (Dappen et al., 2026)