Body

in their 2026 literature review, Melanthiou describes how Hyperacusis, tinnitus, and misophonia share increased central auditory gain and hyperactivity in regions like the inferior colliculus (IC), auditory cortex, and salience network (anterior insula, ACC), suggesting hyperacusis may act as a general sensory hypersensitivity that amplifies symptom severity and distress in the other conditions (Melanthiou et al., 2026 ).