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a 2015 case study showed marginal improvements in Misophonic physical symptoms using a counterconditioning approach to treat reflexive muscle resposnes to a specific trigger

In a 2015 case report, Dozier presented the results of a counterconditioning approach to treating misophonia. Operating under the framework of misophonia as a conditioned reflex disorder, Dozier employed the Neural Repatterning Technique (NRT) in combination with Progressive Muscle Relaxation (PMR), delivered via a custom mobile app. The intervention paired individualized trigger sounds with positive stimuli, such as soothing music. Over the course of seven days, the patient's physical reflex response was significantly reduced, and her emotional responses also diminished, even though they were not directly targeted. Based on these outcomes, Dozier proposed that this supported a model of misophonia in which the emotional response follows from an initial physical reflex. (Dozier, 2015)