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ADHD and GAD Most Common Comorbidities; OCD and PTSD Rare

In a 2024 study, Woolley attempted to characterize the onset, symptom progression, triggers, and psychiatric comorbidities in treatment-seeking adults with misophonia by conducting structured clinical interviews (Duke Misophonia Interview and DIAMOND) and administering self-report questionnaires to 60 adults meeting clinical criteria for misophonia. they found that ADHD was the most prevalent comorbidity (23%), followed by generalized anxiety disorder (17%), with 52% meeting no criteria for another psychiatric disorder. OCD and PTSD each occurred in only 3% or fewer participants, challenging historical speculation linking these conditions to misophonia. The presence of any psychiatric comorbidity did not predict overall misophonia severity, likely due to heterogeneity in comorbid conditions. These findings suggest misophonia should be treated as a distinct disorder rather than a variant of OCD or trauma-related conditions (Woolley et al., 2024).